Tesamorelin Injections


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Tesamorelin Peptide Review: What is Tesamorelin, and what is it for?

If you are an ardent bodybuilder or aspiring to be one, you may have come across a drug called Tesamorelin, also known by its brand name Egrifta. Although this drug has been around since 2010, it has become increasingly popular for its ability to increase growth hormone production in the body.

This increase comes with benefits such as increased muscle mass and fat loss.  This Tesamorelin review tells you more about this drug that can shrink away unwanted belly fat to reveal the toned abs underneath.

Tesamorelin is part of ‘peptide therapy’ that has taken the health and fitness worlds by storm. Peptide therapy refers to using peptides to trigger or encourage body cells to perform or become more effective at performing various specific functions.

Depending on the particular peptide, these functions could be muscle building, cognitive function, weight loss, improving the immune system, etc. Other common peptides that you are likely to encounter as you explore peptide therapy are Ipamorelin and BPC 157.

Which brings us to the next point- what are peptides? Peptides are short-chain amino acids made up of two to fifty chains.  These chains are bound together by peptide bonds. They are quite similar to proteins, with the significant difference being that proteins have longer chains of more than 50 amino acids. Tesamorelin, for instance, is made up of 44 amino acid chains. 

Peptides are naturally produced in the body, where they perform various biological functions. They act as building blocks for enzymes and hormones and also instruct other cells and molecules on what functions to perform.


What is Tesamorelin?

Tesamorelin is a synthetic peptide hormone that acts as a growth hormone-releasing factor (GHRF). This means that it stimulates the pituitary gland to release the growth hormone into the bloodstream.  

On the other hand, the human growth hormone is a hormone produced by the pituitary gland located at the base of the brain. Its primary role is to spur muscle growth, boost metabolism, support cell repair, and promote fat loss, among other benefits.

Low levels of the growth hormone, for instance, are linked to higher amounts of belly fat.  Tesamorelin is one of the most significant growth hormones stimulating peptides available.


What is the origin of Tesamorelin Peptide?

Tesamorelin was approved by the FDA in November 2010 as a drug to reduce fat accumulation in people with HIV. This is because HIV medication was seen to increase fat in certain body parts, particularly the belly and back areas.

Although used to decrease fat in the body, Tesamorelin is not a fat loss drug, but rather, it is a human growth hormone-releasing factor analog. Its ability to target fat loss in particular areas such as the belly makes it attractive to bodybuilders and other fitness enthusiasts.

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How does Tesamorelin work?

As mentioned, Tesamorelin is a synthetic version of the human growth releasing hormone, which is naturally produced in the hypothalamus. Once the Tesamorelin peptide is injected into the body, it stimulates the pituitary gland to release the growth hormone into the bloodstream.

The growth hormone then goes to work to boost metabolism, leading to better fat utilization and, therefore, reducing abdominal fat. It also increases protein production and increases energy levels. This can lead to bigger muscle growth and enhanced endurance.

What happens when human growth hormone levels are low?

The growth hormone (GH) is required for various vital processes in the body. It supports metabolism; the process by which the food we eat is turned into energy in the body. GH also increases muscle mass, strength, and reduces body fat.

As we age, our growth hormone levels start to decline, sometimes as early as the age of 30. This can result in fatigue, slower recovery times, fat increase particularly in the belly and muscle mass loss. Similarly, low GH levels can lead to depression and loss of libido. Increased production of this crucial hormone can reverse most of these effects.


What are the benefits of Tesamorelin?

Tesamorelin stimulates the production of the human growth hormone, which gives the following benefits:

  •         It reduces visceral fat around the belly
  •         It accelerates metabolism, which leads to further weight loss
  •         It optimizes energy use in the body
  •         It promotes muscle growth and strength
  •         It improves cognitive function
  •         It increases the insulin growth factor (IGF-1)
  •         Faster recovery time from strenuous workouts
  •         It reduces fat accumulation in the liver, promoting overall health

What Tesamorelin side effects should I look out for?

Although peptides are considered generally safe, you should be aware that Tesamorelin can cause some side effects.  If you are taking other medication, you should consult a doctor before taking this peptide as it is known to interact with certain medications. Similarly, pregnant women and those with diabetes should not take Tesamorelin. Some of the side effects to look out for are:

  •         Muscle pain
  •         Swelling or redness at the injection site
  •         Headaches
  •         Nausea
  •         Itching
  •         Vomiting
  •         Night sweats
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Tesamorelin Protocols, Dosages and Administration

Tesamorelin is sold in powder form and must be mixed with water (reconstituted) before use. Similar to other peptides, Tesamorelin is highly fragile and must be gently mixed with sterilized water. Once reconstituted, it should be stored in the refrigerator and used within the recommended period.

This drug is administered subcutaneously through injection. Your physician should advise you on a safe dose depending on your needs, but a dose of 2mg once a day is standard. If you are using it as a bodybuilding and fat loss aid, you may get better results by combining it with a good diet and strength workout regime.


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Tesamorelin Injections- Frequently Asked Questions

If you are learning about this growth hormone stimulating peptide for the first time, you may have some lingering questions. We have tried to answer these below:

Is Tesamorelin legal?

Yes, Tesamorelin is legal and approved by the FDA to reduce excess body in the stomach and abdomen of people living with HIV. Because of its ability to mimic the effects of the growth hormone, it is now used in health and sports to increase muscle mass, energy, endurance, and reduce fat accumulation in the body. Because peptides enhance performance, their use is banned in competitive sport.

Do I require a prescription for Tesamorelin?

Yes, Tesamorelin is only available through prescription. You can get a prescription from your naturopathic clinic or physician. This will be done after a series of blood tests or other necessary testing to establish your needs. When you buy the peptide online, ensure that you only do so from a reputable source that stocks authentic peptides from licensed and accredited pharmacies. You can never be too careful with something that you put in your body. 

How long does it take Tesamorelin to work?

This varies from person to person, depending on various factors such as your body’s metabolism and the overall state of health. Online reports from people who have used it seem to suggest that results show in about three months. As mentioned, you will see better results if you combine it with a proper diet and regular exercise.

How should this medicine be used?

Tesamorelin should be injected subcutaneously (under the skin) either in the stomach or abdomen. It should not be injected in the navel or a bruised area. As it is sold in powder form, it must be reconstituted before use. You can also combine Tesamorelin with another peptide such as Ipamorelin. Even then, ensure that you follow the doctor’s instructions regarding dosage.

The best recommended time to take Tesamorelin is in the evening, just before bed. This is useful as the drug will mimic your body’s natural production of the growth hormone, which peaks at night.

Does Tesamorelin burn fat?

Yes, Tesamorelin burns fat by stimulating the production of the human growth hormone, which accelerates metabolism and more effective utilization of fat deposits in the body. This leads to fat loss, particularly around the belly area. Tesamorelin also increases energy and stamina. The more energy you have, the more you will lift heavier weights or work out longer, leading to sustained fat burning.

Tesamorelin Vs. Ipamorelin

 Both Tesamorelin and Ipamorelin are synthetic peptides that encourage the release of the human growth hormone. Ipamorelin is made up of five amino acid chains, making it a short peptide that is fast-acting. Tesamorelin has 44 amino acid chains making it a longer-acting peptide.

 One significant difference between the two is that they work in different pathways in the body. Tesamorelin acts on the growth hormone-secreting receptors, while Ipamorelin triggers the ghrelin receptors. This means that you can combine the two peptides to get more benefits from both pathways.

What precautions should I keep in mind regarding Tesamorelin?

Tesamorelin is a human growth hormone-releasing factor, and as such, it is not a medication for obesity or a weight loss aid. It increases growth hormone production, which comes with increased muscle mass and belly fat reduction. 

You should not take this peptide if you are pregnant or have a history of tumors. Similarly, you should let your doctor know if you have any pre-existing chronic conditions such as diabetes, high blood pressure, and heart disease.